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Coding and Billing Information

The importance of simplified, accurate coding and billing is second only to the vaccines themselves. flu360™ helps navigate complexities-CPT codes, NDC numbers, coding based on payer, and more-to aid in the reimbursement process.

Seqirus Portfolio Coding and Billing Guide

Consider this your go-to coding and billing resource for our portfolio of vaccines

You can access CPT codes as well as administrative coding details, such as HCPCS codes, ICD-10 codes, and modifier 25 guidance.

Have reimbursement-related questions?
Call flu360 | Support at 855-358-8966, option 2.

Download
Seqirus Portfolio Coding and Billing Guide

Quick Coding Reference

Easily find CPT codes, NDC numbers, CVX codes, and more.*

FLUAD® QUADRIVALENT

Flucelvax® QUADRIVALENT

Afluria® QUADRIVALENT

Seqirus Vaccine
Product Description		 Presentation/
Dose1 		Age
Indication1		 Vaccine Product
CPT Code2		 2021-2022
NDC Unit-of-Use2		 2021-2022
NDC Carton2		 CVX
Code†2
FLUAD®
QUADRIVALENT
(Influenza Vaccine,
Adjuvanted)		 Pre-filled
syringe 0.5 mL		 65 years
and older		 90694 70461-121-04 70461-121-03 205
Download FLUAD® QUADRIVALENT Guide for more vaccine-specific detailsDownload
Seqirus Vaccine
Product Description		 Presentation/
Dose3 		Age
Indication3		 Vaccine Product CPT Code2 2021-2022
NDC Unit-of-Use2		 2021-2022
NDC Carton2		 CVX
Code†2
FLUCELVAX® QUADRIVALENT
(Influenza Vaccine)		 Pre-filled
syringe 0.5 mL		 6 months
and older		 90674 70461-321-04 70461-321-03 171
Multi-dose viala
5 mL		 6 months
and older		 90756 70461-421-11 70461-421-10 186
Download FLUCELVAX® QUADRIVALENT Guide for more vaccine-specific detailsDownload
Seqirus Vaccine
Product Description		 Presentation/
Dose4 		Age Indication4 Vaccine Product CPT Code2 2021-2022
NDC Unit-of-Use2		 2021-2022
NDC Carton2		 CVX
Code†2
AFLURIA®
QUADRIVALENT
(Influenza Vaccine)		 Pre-filled
syringe 0.25 mL		 6 through
36 months		 90685 33332-221-21 33332-221-20 161
Pre-filled
syringe 0.5 mL		 36 months
and older		 90686 33332-321-01 33332-321-01 150
Multi-dose vialb
5 mL		 6 through
35 months		 90687 (0.25-mL dose) 33332-421-11 33332-421-11 158
36 months
and older		 90688 (0.5-mL dose)
Download AFLURIA® QUADRIVALENT Guide for more vaccine-specific detailsDownload
  • FLUAD® QUADRIVALENT Expand

    FLUAD® QUADRIVALENT
    (Influenza Vaccine, Adjuvanted)

    • Presentation/Dose4

      Pre-filled syringe 0.5 mL

    • Age Indication4

      65 years and older

    • Vaccine Product CPT Code2

      90694

    • 2021-2022 NDC Unit-of-Use2

      70461-121-04

    • 2021-2022 NDC Carton2

      70461-121-03

    • CVX Code†2

      205

    Download FLUAD
    QUADRIVALENT Guide for
    more vaccine-specific detailsDownload

    90694=Influenza virus vaccine, quadrivalent (aIIV4), inactivated, adjuvanted, preservative free, 0.5-mL dosage, for intramuscular use

  • Flucelvax®
    QUADRIVALENT Expand

    FLUCELVAX® QUADRIVALENT
    (Influenza Vaccine)

    • Presentation/Dose4

      Pre-filled syringe 0.5 mL

    • Age Indication4

      6 months and older

    • Vaccine Product CPT Code2

      90674

    • 2021-2022 NDC Unit-of-Use2

      70461-321-04

    • 2021-2022 NDC Carton2

      70461-321-03

    • CVX Code†2

      171

    • Presentation/Dose4

      Multi-dose viala 5 mL

    • Age Indication4

      6 months and older

    • Vaccine Product CPT Code2

      90756

    • 2021-2022 NDC Unit-of-Use2

      70461-421-11

    • 2021-2022 NDC Carton2

      70461-421-10

    • CVX Code†2

      186

    Download FLUCELVAX
    QUADRIVALENT Guide for
    more vaccine-specific detailsDownload

    90674=Influenza virus vaccine, quadrivalent (ccIIV4), derived from cell cultures, subunit, preservative and antibiotic free, 0.5-mL dosage, for intramuscular use
    90756=Influenza virus vaccine, quadrivalent (ccIIV4), derived from cell cultures, subunit, antibiotic free, 0.5-mL dosage, for intramuscular use
    a No more than 10 doses (0.5 mL) should be withdrawn from the FLUCELVAX QUADRIVALENT multi-dose vial.

  • Afluria® QUADRIVALENT Expand

    AFLURIA® QUADRIVALENT
    (Influenza Vaccine)

    • Presentation/Dose4

      Pre-filled syringe 0.25 mL

    • Age Indication4

      6 through 35 months

    • Vaccine Product CPT Code2

      90685

    • 2021-2022 NDC Unit-of-Use2

      33332-221-21

    • 2021-2022 NDC Carton2

      33332-221-20

    • CVX Code†2

      161

    • Presentation/Dose4

      Pre-filled syringe 0.5 mL

    • Age Indication4

      36 months and older

    • Vaccine Product CPT Code2

      90686

    • 2021-2022 NDC Unit-of-Use2

      33332-321-02

    • 2021-2022 NDC Carton2

      33332-321-01

    • CVX Code†2

      150

    • Presentation/Dose4

      Multi-dose vialb 5 mL

    • Age Indication4

      6 through 35 months

      36 months and older

    • Vaccine Product CPT Code2

      90687 (0.25-mL dose)

      90688 (0.5-mL dose)

    • 2021-2022 NDC Unit-of-Use2

      33332-421-11

    • 2021-2022 NDC Carton2

      33332-421-10

    • CVX Code†2

      158

    Download AFLURIA
    QUADRIVALENT Guide for
    more vaccine-specific detailsDownload

    90685=Influenza vaccine, quadrivalent (IIV4), split virus, preservative-free, 0.25-mL dosage, for intramuscular use

    90686=Influenza vaccine, quadrivalent (IIV4), split virus, preservative-free, 0.5-mL dosage, for intramuscular use

    90687=Influenza vaccine, quadrivalent (IIV4), split virus, 0.25-mL dosage, for intramuscular use

    90688=Influenza vaccine, quadrivalent (IIV4), split virus, 0.5-mL dosage, for intramuscular use bNo more than 10 doses (0.25 mL or 0.5 mL) should be withdrawn from the AFLURIA QUADRIVALENT multi-dose vial.

*This information does not constitute a guarantee or warranty of coverage benefits or reimbursement.

†CVX=vaccine administered code indicates which product was used and is used in combination with the manufacturer (MVX) code. The MVX code for Seqirus is SEQ.

Coding is less complex with a little help

Follow this example form, and find more examples when you download our comprehensive Seqirus Coding and Billing Guide.1,5-8

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If required by payer, 11-digit NDC format using the carton NDC. If payer requires NDC, use the “N4” qualifier immediately, followed by the 11-digit carton NDC, followed by the qualifier “ML” for milliliter and the quantity as shown in the shaded area

Coding and billing sample form highlighting NDC code

R29.6=repeated falls

Coding and billing sample form highlighting repeated falls

Refer back to the appropriate diagnosis code on each line, including the vaccine and the vaccine administration

Coding and billing sample form highlighting diagnosis pointer

Z23=encounter for immunization

Coding and billing sample form highlighting encounter for immunization

99203=office or other outpatient visit for the E&M of a new patient

Coding and billing sample form highlighting office or outpatient visit for new patient

90694=FLUAD QUADRIVALENT

Coding and billing sample form highlighting code for FLUAD QUADRIVALENT flu vaccine

G0008=administration

Coding and billing sample form highlighting code for vaccine administration

25=modifier (See page 6: Code for the administration service)

Coding and billing sample form highlighting code for modifier 25
Coding and billing sample form highlighting NDC code

If required by payer, 11-digit NDC format using the carton NDC. If payer requires NDC, use the “N4” qualifier immediately, followed by the 11-digit carton NDC, followed by the qualifier “ML” for milliliter and the quantity as shown in the shaded area

Coding and billing sample form highlighting repeated falls

R29.6=repeated falls

Coding and billing sample form highlighting diagnosis pointer

Refer back to the appropriate diagnosis code on each line, including the vaccine and the vaccine administration

Coding and billing sample form highlighting encounter for immunization

Z23=encounter for immunization

Coding and billing sample form highlighting office or outpatient visit for new patient

99203=office or other outpatient visit for the E&M of a new patient

Coding and billing sample form highlighting code for FLUAD QUADRIVALENT flu vaccine

90694=FLUAD QUADRIVALENT

Coding and billing sample form highlighting code for vaccine administration

G0008=administration

Coding and billing sample form highlighting code for modifier 25

25=modifier (See page 6: Code for the administration service)

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Featured Resources

Seqirus Portfolio Coding and Billing Guide

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References: 1. FLUAD QUADRIVALENT. Package insert. Seqirus Inc; 2020. 2. Centers for Disease Control and Prevention. CPT codes mapped to CVX codes. Accessed February 18, 2021. https://www2a.cdc.gov/vaccines/iis/iisstandards/vaccines.asp?rpt=cpt 3. FLUCELVAX QUADRIVALENT. Package insert. Seqirus Inc; 2021. 4. AFLURIA QUADRIVALENT. Package insert. Seqirus Inc; 2020. 5. American Academy of Family Physicians. Medicare Part B and Part D vaccine coverage. Accessed November 18, 2020. https://www.aafp.org/family-physician/practice-and-career/getting-paid/coding/medicare-vaccine-coverage.html 6. Procedural Coding Expert: The Ultimate Guide to CPT® Coding. Contexo Media; 2013. 7. Centers for Medicare & Medicaid Services. ICD-10-CM tabular list of diseases and injuries. Accessed November 18, 2020. https://www.cms.gov/Medicare/Coding/ICD10/Downloads/2020-ICD-10-CM-Code-Tables.zip

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AFLURIA® QUADRIVALENT, flu360TM, FLUAD® QUADRIVALENT, FLUCELVAX® QUADRIVALENT, MF59®, and WE'VE GOT FLU COVEREDTM are trademarks of Seqirus UK Limited or its affiliates.

Manufactured by: Seqirus Inc., 475 Green Oaks Parkway, Holly Springs, NC 27540, USA

Distributed by: Seqirus USA Inc., 25 Deforest Avenue, Summit, NJ, 07901, USA

©2021 Seqirus USA Inc. November 2021 USA-FLU360-21-0225, USA-FLU360-21-0004, USA-FLU360-21-0226, USA-FLU360-21-0009, USA-FLU360-21-0010, USA-FLU360-21-0011, USA-FLU360-21-0012, USA-FLU360-21-0013, USA-FLU360-21-0014, USA-FLU360-21-0227